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Postdoctoral or Staff Position to Study Oral Microbiome Genetics and Polymicrobial Infections

Oregon Health & Science University
Portland, Oregon, United States
30+ days ago

Description

Dept/Division:                     Restorative Dentistry

Primary Dept Rank:            Postdoctoral Researcher or Research Associate                                                              

Term:                                    12-month contract (renewable annually)               

Annual Salary (1.0 FTE):    Commensurate with experience                                                                                

Position Description:          Postdoctoral or staff position available immediately in the Merritt Lab for genetic studies of the human oral microbiome.

The Merritt Laboratory studies the human oral microbiome as a tractable model system to characterize the host-flora mechanisms responsible for mucosal dysbiotic diseases. We research the genetics of a variety of oral microbiome species isolated from clinical specimens, and more recently, we have developed a new mixed species polymicrobial infection model useful for revealing the mechanisms of polymicrobial synergism in oral dysbiotic diseases. Current research in the lab: 1) studies of oral bacterial genetics – isolate understudied microbiome species directly from clinical specimens, develop new microbiome genetic systems, and examine the genetic mechanisms mediating microbe-microbe and microbe-host interactions; and 2) studies of polymicrobial synergistic pathogenesis – isolate novel host-targeting bioactivities directly from oral microcosm biofilm communities, characterize microbiome interactions with epithelial and immune cells, and investigate mouse genetics and immunopathology in a murine model of polymicrobial infections.

Candidates should be highly self-motivated and possess a strong background in microbial genetics, molecular biology, biochemistry, immunology, or a related field.

Typical duties of this position include:

genetic mutation construction, gene expression analysis, protein expression/purification, EMSA, Co-IP, cryo-EM, northern blotting, western blotting, FACS analysis, and fluorescence microscopy.



Requirements

Position Conditions/Qualifications:

Required

  • Evidence of extensive experience with current genetic, molecular biology, and/or biochemistry techniques
  • Excellent verbal and written communication skills
  • Ability to work independently and as part of a team

Preferred

  • Doctoral degree in a related field of science
  • Microbial ecology and/or bacteriology experience
  • Experience working with RNA
  • Protein purification and structure determination
  • Strong background in gene regulation and/or post-transcriptional regulation
  • Experience handling mice
  • Ability to contribute to the writing of scientific papers and/or grants

Apply online at https://www.ohsu.edu/human-resources/job-application-website

iCIMS 2021-11559 or 2021-11560

For additional details or further inquiry, please contact:

Justin Merritt, Ph.D.

Professor

Oregon Health and Science University

3181 SW Sam Jackson Park Rd. MRB424

Portland, OR 97239

https://www.ohsu.edu/people/justin-l-merritt-phd

Job Information

  • Job ID: 59373867
  • Location:
    Portland, Oregon, United States
  • Position Title: Postdoctoral or Staff Position to Study Oral Microbiome Genetics and Polymicrobial Infections
  • Company Name: Oregon Health & Science University
  • Job Function: Research
  • Job Type: Postdoctoral Fellowship
  • Job Duration: Indefinite
  • Min Education: Master's Degree
  • Required Travel: 0-10%

Please refer to the company's website or job descriptions to learn more about them.

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